TLR5 anticorps (AA 81-766)

N° du produit ABIN7602531

Cet anticorps Lapin Polyclonal détecte spécifiquement TLR5 dans WB et ELISA. Il présente une réactivité envers Souris et Rat.

Aperçu rapide pour TLR5 anticorps (AA 81-766) (ABIN7602531)

Antigène: TLR5 (Toll-Like Receptor 5 (TLR5))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR5 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TLR5 anticorps

Épitope: AA 81-766

Fonction: Anti-Tlr5 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-Tlr5 Antibody Picoband® (ABIN7602531). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse Tlr5 recombinant protein (Position: Q81-D766).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Andersen-Nissen, E., Hawn, T. R., Smith, K. D., Nachman, A., Lampano, A. E., Uematsu, S., Akira, S., Aderem, A. Cutting edge: Tlr5-/- mice are more susceptible to Escherichia coli urinary tract infection. J. Immun. 178: 4717-4720, 2007. 2. Andersen-Nissen, E., Smith, K. D., Bonneau, R., Strong, R. K., Aderem, A. A conserved surface on Toll-like receptor 5 recognizes bacterial flagellin. J. Exp. Med. 204: 393-403, 2007. 3. Burdelya, L. G., Krivokrysenko, V. I., Tallant, T. C., Strom, E., Gleiberman, A. S., Gupta, D., Kurnasov, O. V., Fort, F. L., Osterman, A. L., DiDonato, J. A., Feinstein, E., Gudkov, A. V. An agonist of Toll-like receptor 5 has radioprotective activity in mouse and primate models. Science 320: 226-230, 2008.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur TLR5

Antigène: TLR5 (Toll-Like Receptor 5 (TLR5))

Autre désignation: Tlr5

Sujet:

Synonyms: Beta-2-microglobulin, B2m

Tissue Specificity: Detected in lung, spleen, uterus, vagina and epididymis. .

Background: Toll-like receptor 5, also known as TLR5, is a protein which in humans is encoded by the TLR5 gene. Predicted to enable interleukin-1 receptor binding activity and signaling receptor activity. Predicted to be involved in several processes, including positive regulation of interleukin-8 production, positive regulation of nitric oxide biosynthetic process, and positive regulation of toll-like receptor signaling pathway. Predicted to act upstream of or within innate immune response. Predicted to be located in membrane. Predicted to be integral component of plasma membrane. Is expressed in brain, olfactory epithelium, spinal cord, and trunk unsegmented mesenchyme. Human ortholog(s) of this gene implicated in Legionnaires' disease, cystic fibrosis, cystitis, melioidosis, and systemic lupus erythematosus. Orthologous to human TLR5 (toll like receptor 5).

Poids moléculaire: 100 kDa

ID gène: 53791

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades